KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLCC1
All Species:
8.79
Human Site:
T469
Identified Species:
27.62
UniProt:
Q96S66
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96S66
NP_001041675.1
551
62023
T469
H
K
S
P
V
L
D
T
K
P
K
E
T
G
G
Chimpanzee
Pan troglodytes
XP_513612
551
62116
T469
H
K
S
P
V
L
D
T
K
P
K
E
T
G
G
Rhesus Macaque
Macaca mulatta
XP_001087523
551
62145
T469
Q
K
S
P
V
L
D
T
K
P
K
E
T
G
G
Dog
Lupus familis
XP_537044
512
58239
P431
M
V
P
G
H
K
L
P
V
L
D
T
K
P
K
Cat
Felis silvestris
Mouse
Mus musculus
Q99LI2
539
60603
K458
P
E
V
V
P
S
H
K
S
P
I
M
N
T
N
Rat
Rattus norvegicus
Q9WU61
541
61155
V459
A
Q
E
H
P
E
V
V
P
S
H
K
P
S
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505350
581
65207
Q469
H
L
G
Q
R
V
T
Q
T
Q
E
E
T
T
Q
Chicken
Gallus gallus
Frog
Xenopus laevis
Q91892
508
57895
N426
P
R
D
N
D
V
V
N
I
P
K
Q
Q
P
L
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
96.3
75.5
N.A.
72.5
73.5
N.A.
48.1
N.A.
39.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
97.4
81.3
N.A.
82.4
83.3
N.A.
61.6
N.A.
59.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
0
N.A.
6.6
0
N.A.
20
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
0
N.A.
13.3
13.3
N.A.
33.3
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
13
0
13
0
38
0
0
0
13
0
0
0
0
% D
% Glu:
0
13
13
0
0
13
0
0
0
0
13
50
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
13
13
0
0
0
0
0
0
0
0
0
38
38
% G
% His:
38
0
0
13
13
0
13
0
0
0
13
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
13
0
13
0
0
0
13
% I
% Lys:
0
38
0
0
0
13
0
13
38
0
50
13
13
0
13
% K
% Leu:
0
13
0
0
0
38
13
0
0
13
0
0
0
0
13
% L
% Met:
13
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% M
% Asn:
0
0
0
13
0
0
0
13
0
0
0
0
13
0
13
% N
% Pro:
25
0
13
38
25
0
0
13
13
63
0
0
13
25
0
% P
% Gln:
13
13
0
13
0
0
0
13
0
13
0
13
13
0
13
% Q
% Arg:
0
13
0
0
13
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
38
0
0
13
0
0
13
13
0
0
0
13
0
% S
% Thr:
0
0
0
0
0
0
13
38
13
0
0
13
50
25
0
% T
% Val:
0
13
13
13
38
25
25
13
13
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _